• Clinical validation of a new “call-out algorithm” for postoperative pain management: a two-center prospective randomized trial 

      Kuklin, Vladimir; Dybvik, Lisa; Skraastad, Erlend Johan; Yeltayeva, Aigerim; Konkayev, Aidos; Musaeva, Tatiana; Zabolotskikh, Igor; Bjertnaes, Lars J.; Dahl, Vegard; Ræder, Johan (Conference object; Konferansebidrag, 2017-05-06)
      The goal of modern postoperative pain management is to relieve pain while keeping side effects to a minimum. Still, in recent investigations, between 20% and 40% of all postoperative patients report high levels of pain after surgery, while 20-30% experience adverse effects of opioid analgetics [1,2]. In a study, in which the hospitals had introduced pain management guided by the patients' own ...
    • Influence of a New “Call-Out Algorithm” for Management of Postoperative Pain and Its Side Effects on Length of Stay in Hospital: A Two-Centre Prospective Randomized Trial 

      Dybvik, Lisa; Skraastad, Erlend Johan; Yeltayeva, Aigerim; Konkayev, Aidos; Musaeva, Tatiana; Zabolotskikh, Igor; Bjertnaes, Lars J.; Dahl, Vegard; Ræder, Johan; Kuklin, Vladimir (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-10)
      Background. We recently introduced the efficacy safety score (ESS) as a new “call-out algorithm” for management of postoperative pain and side effects. In this study, we report the influence of ESS recorded hourly during the first 8 hours after surgery on the mobility degree, postoperative nonsurgical complications, and length of hospital stay (LOS). Methods. We randomized 1152 surgical patients ...
    • Physiological Changes in Subjects Exposed to Accidental Hypothermia: An Update 

      Bjertnaes, Lars J.; Næsheim, Torvind; Reierth, Eirik; Suborov, Evgeny; Kirov, Mikhail; Lebedinskii, Konstantin M.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-23)
      Background: Accidental hypothermia (AH) is an unintended decrease in body core temperature (BCT) to below 35°C. We present an update on physiological/pathophysiological changes associated with AH and rewarming from hypothermic cardiac arrest (HCA).<p> <p>Temperature Regulation and Metabolism: Triggered by falling skin temperature, Thyrotropin-Releasing Hormone (TRH) from hypothalamus induces ...
    • Prioritized brain circulation during ergometer cycling with apnea and face immersion in ice-cold water: A case report 

      Bjertnaes, Lars J.; Hauge, Anton; Thoresen, Marianne; Walløe, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-24)
      Background: Successful cardiopulmonary resuscitation after drowning or avalanche is often attributed to hypothermia-induced decrease in metabolism, which adapts the oxygen demand to the amount supplied under cardiac compression. Four decades ago, we speculated if oxygen-sparing mechanisms like those found in marine mammals, may improve cerebral oxygenation during acute airway blockade in humans. We ...
    • Thromboelastometry for Assessing Risks of Free Flap Thrombosis in Patients Undergoing Microvascular Surgery 

      Vanags, Indulis; Stepanovs, Jevgenijs; Ozolina, Agnese; Mukans, Maksims; Bjertnaes, Lars J.; Mamaja, Biruta (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-23)
      <p>Introduction</i>: Coagulation assessment is often missing in microvascular surgery. We aimed at evaluating the predictive value of thromboelastometry for free flap thrombosis in microvascular surgery patients.<p> <p> <i>Materials and Methods</i>: We enrolled 103 adult patients with traumatic injuries scheduled for microvascular free flap surgery into a prospective observational study. Thirty-six ...